Endless Vitality
Endless Vitality

Pentosan Polysulphate Sodium (PPS)

Updated Jul 24, 2025

PPS is thought to work partly through its anti–clotting properties by shifting oedema and improving blood flow to the damaged area and partly
through its anti-inflammatory action. Paradigm Biopharma are claiming that about 90% of the patients with knee arthritis they have treated are
reported good relief.

Benefits
: Pentosan polysulfate is commonly used for the relief of osteoarthritis. The mechanism of PPS action in osteoarthritis is multifactorial,
with both stimulation of cartilage synthesis and aids in the prevention of cartilage breakdown. In one study they found that Pentosan
increases both the production and the molecular weight of hyaluronan.
Content & Potency
Injectable
500mg Vial: Reconstitute 5ml with BWFI (100mg/ml – 5ml)
Inject 0.10ml – 0.20ml subcutaneously once daily

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